产品型号:GM-J#008200 -Cryorecovery
产品应用:These piGAP transgenic reporter mice have expression of the eGFP-F-IRES-hPLAP dicistronic gene blocked by an upstream loxP-flanked STOP-polyA sequence. When bred to mice that express Cre recombinase, the resulting offspring will have the STOP-polyA sequence deleted in the cre-expressing tissue(s), permitting dicistronic expression of human Placental Alkaline Phosphatase (PLAP or ALPP) and farnesylated Enhanced Green Fluorescent Protein (eGFP-F; optimized to target expression to the cytoplasmic side of the plasma membrane). These piGAP transgenic reporter mice allow Cre-inducible, eGFP-F and hPLAP expression in multiple cell and tissue types.