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  • B6.Cg-Tg(Itgax-cre)

    产品型号:GM-J#008068 -Available

    产品应用:Mice harboring the Itgax-cre (Cd11c-Cre) BAC transgene express Cre recombinase under control of the integrin alpha X gene (Itgax or Cd11c) promoter/enhancer regions within the BAC transgene. These Cd11c-Cre transgenic mice are a Cre-lox tool for deletion of floxed sequences in CD8-, CD8+ dendritic cells, tissue-derived dendritic cells from lymph nodes, lung and epidermis, as well as plasmacytoid dendritic cells. This strain may be useful for studying dendritic cell homeostasis and function.

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