产品型号：GM-J#006582 -Available

产品应用：Parkin knock-out mice (homozygous) have increased extracellular dopamine concentration in the striatum, dysfunctional nigrostriatal pathways, and dysfunctional mitochondria. These mice model the exon 3 deletion mutation most common in human autosomal recessive juvenile parkinsonism (AR-JP; Parkinson disease 2; PARK2) patients and may be useful in studies of Parkinson's disease, dopamine regulation, nigrostriatal function, mitochondrial function, and other neurobiological research.