产品型号：GM-J#005107 -Available

产品应用：These transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the human keratin 14 (KRT14) promoter, which is active in dividing cells of epidermis and some other stratified squamous epithelia. When crossed with a strain containing a loxP site flanked sequence of interest, the offspring can be used to generate tamoxifen-induced, Cre-mediated targeted keratinocyte-specific deletions. This strain may be useful for studying somatic mutations of the skin, including squamous and basal cell carcinomas.