产品型号:GM-J#068059-JAX -Cryorecovery
产品应用:Pou3f4 knock-in/knock-out mice contain a Cre recombinase that replaces the Pou3f4 (POU domain, class 3, transcription factor 4) coding region. Females homozygous for the mutation and males hemizygous for the X-linked mutation are deaf due to reduced endocochlear potential; mutants also show a failure of auditory spiral ganglion neuron radial bundle fasciculation and synapse formation in the cochlea.