产品型号：GM-J#039167 -Available For Pre-Order

产品应用：Humanized A53T SNCA-GR (gene replacement) mice are a knock-in/knock-out model in which the mouse genomic region from Snca (synuclein, alpha) is exchanged for 158 kb of the human SNCA genomic region including the A53T mutation. A53T is associated with early-onset Parkinson's disease (PD). This strain may be used to explore more fully the role of SNCA in Parkinson's disease (PDD), dementia with Lewy bodies (DLB), multiple system atrophy (MSA), and Alzheimer's disease.