产品型号：GM-J#039166 -Available For Pre-Order

产品应用：Humanized wildtype SNCA-GR (gene replacement) mice are a knock-in/knock-out model in which the mouse genomic region from Snca (synuclein, alpha) is exchanged for 158 kb of the human SNCA genomic region. These mice may serve as base models into which additional alterations can be introduced to explore more fully the role of SNCA in Parkinson's disease (PDD), dementia with Lewy bodies (DLB), multiple system atrophy (MSA), and Alzheimer's disease.