产品型号：GM-J#039003 -Available For Registering Interest

产品应用：FLIM-compatible A Kinase Activity Reporter (FL-AK, FLIM-AKARflox) mice express the FLIM-AKAR optical fluorescent reporter in a Cre-dependent manner. Cre recombinase-mediated excision of a loxP-flanked Stop cassette enables the observation of protein kinase A (PKA) activity with cellular resolution in real time. This strain has been useful in revealing PKA activity dynamics in genetically defined cell types via fluorescence lifetime imaging microscopy (FLIM) or photometry in brain slices and in vivo.