产品型号：GM-J#038495 -Available For Registering Interest

产品应用：Gli1-CreER knock-in/knock-out mice express a CreER fusion protein driven by the GLI-Kruppel family member GLI1 (Gli1) endogenous promoter, while abolishing endogenous Gli1 expression. When these mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in the Gli1-expressing cells of the offspring. These mice may be useful for studying axis patterning, proliferation, and cell fate specification of Hedgehog responding cells at different stages of embryogenesis.