产品型号：GM-J#038446 -Available For Pre-Order

产品应用：TetP-hA53T α-syn (line 4360) transgenic mice expresses the mutant human A53T alpha-synuclein under the control of the mouse prion protein (Prnp) gene promoter and the tetO, tetracycline-responsive regulatory element. When mated to a mutant strain expressing tTA, expression of SNCA*A53T protein may be regulated with the tetracycline analog doxycycline in the double mutant offspring. These mice may be useful in studying human neuronal alpha-synucleinopathies, such as familial Parkinson's Disease.