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  • STOCK Igs7tm2(tetO-GCaMP8s,CAG-tTA2)

    产品型号:GM-J#037719 -Available

    产品应用:TIGRE2-jGCaMP8s-IRES-tTA2 knock-in mice co-express the jGCaMP8s genetically encoded calcium indicator (GECI) and a tetracycline controlled tetracycline controlled transactivator (tTA2) in a Cre recombinase-dependent manner from the intergenic Igs7 (TIGRE) locus. The addition of an internal ribosome entry site (IRES) introduced upstream of tTA and the omission of a WPRE enhancer element downstream ameliorate previously reported tTA overexpression toxicity issues. jGCaMP8s is a fast rise, medium decay green fluorescent-based GECI with improved sensitivity and faster kinetics.

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