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  • STOCK Gt(ROSA)26Sortm10.1(CAG-birA*,-mKate2)Amc/J

    产品型号:GM-J#037395 -Available

    产品应用:R26 BirA*G3 knock-in mice have a CAG promoter controlling the Cre-inducible expression of a myc-tagged endoplasmic reticulum-directed promiscuous biotin ligase sequence, BirA*G3-ER. Cre-mediated recombination results in the excision of a floxed GFP sequence, enabling the tissue and time-dependent expression of BirA*G3 and mKate2. This is a tool for the isolation and purification of proteins and protein complexes trafficking through the secretory pathway upon biotin administration.

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