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  • B6.Cg-Igs7tm215(CAG-ACR2*,CAG-GCaMP7s)

    产品型号:GM-J#037381 -Cryorecovery

    产品应用:Ai215 (also called Ai215 (TICL-stGtACR2-HA-ICL-GCaMP7s-SS)) is a Cre-dependent optogenetic and fluorescent calcium-indicator tool allele designed with a CAG promoter, loxP-STOP-loxP and stGtACR2 coding sequence followed by a CAG promoter, lox2272-STOP-lox2272 and GCaMP7s coding sequence - all inserted into the Igs7 locus (TIGRE). Exposure to Cre recombinase results in expression of stGtACR2 (soma-targeted variant of the red-shifted, light-gated anion channelrhodopsin GtACR2; neuronal silencing) and/or GCaMP7s fluorescence.

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