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  • B6.Cg-Igs7tm211(tetO-ChrimsonR/tdTomato,CAG-tTA2)

    产品型号:GM-J#037379 -Cryorecovery

    产品应用:Ai211 (also called Ai211(TITL-ChrimsonR-tdT-Kv2.1-ICF-IRES-tTA2)) is a dual-recombinase responsive (cre/flp-dependent), Tet-controllable, fluorescent and optogenetic tool allele created by targeted insertion at the Igs7 locus (TIGRE). Exposure to both Cre and Flp recombinase results in expression of tTA2 and ChrR-tdT (a light-gated cation channel; neuronal activation) in those cells where cre and flp expression overlaps/intersects. ChrR-tdT expression may be expected to be diminished/eliminated by doxycycline.

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