产品型号:GM-J#035169 -Available
产品应用:The inducible KPC:APC mouse model of KRAS mutated colorectal cancer combines the oncogenic conditional KrasG12D allele, the conditional Apcfl allele and a tamoxifen inducible Cre recombinase (CDX2-Cre-ERT2) with cre expression in adult epithelium of the distal intestinal tract. Mice develop malignant colonic tumors 25-30 days post tamoxifen induction.