产品型号：GM-J#035136 -Cryorecovery

产品应用：Cre-inducible-Mps1-Knock-in-TA (CiMKiTA) mice carry a Cre-inducible point mutation (T649A) in exon 17 of the Ttk protein kinase (Ttk) gene, expression of which is blocked by the presence of a loxP-flanked cDNA cassette encoding exons 17-22 and a stop codon. This mutation results in a mutant protein similar to that found in human cell lines with a mild chromosomal instability (CIN) phenotype. This strain may be useful when studying oncogenic potential due to the degree and site of chromosomal instability.