产品型号：GM-J#034694 -Cryorecovery

产品应用：Ai86(TITL-ArcLight) mice are a Cre/Tet-dependent, voltage-sensitive, fluorescent line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). After removal of the floxed-STOP cassette by Cre recombinase, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of the voltage-sensitive fluorescent protein ArcLight. ArcLight exhibits voltage-dependent FRET (Förster resonance energy transfer pairs) upon membrane depolarization, and enables optical recordings at high spatial resolution with intrinsic assignment of recorded signals to targeted cell populations.