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  • B6;129S6-Igs7tm213(CAG-EGFP,CAG-mOrange2,CAG-mKate2)

    产品型号:GM-J#034113 -Cryorecovery

    产品应用:Ai213 (also called Ai213(TICL-EGFP-ICF-mOrange2-ICN-mKate2)) is a triple-recombinase responsive reporter allele designed with a CAG promoter, loxP-STOP-loxP and EGFP coding sequence, followed by a CAG promoter, frt-STOP-frt and mOrange2 coding sequence which is followed by a CAG promoter, nox-STOP-nox and mKate2 coding sequence - all inserted into the Igs7 locus (TIGRE). Exposure to either Cre, FLP or Nigri recombinase results in EGFP fluorescence, mOrange2 fluorescence or mKate2 fluorescence, respectively. In total, Ai213 mice are a Cre::FLP::Nigri intersectional fluorescent reporter line designed to allow EGFP/mOrange2/mKate2 fluorescence in those cells where Cre, FLP and Nigri expression overlaps.

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