产品型号：GM-J#034101 -Cryorecovery

产品应用：Ai173 (also called Ai173(TIT2L-EGFP-HDAC1-ICL-tdT-tTA2)) is a Cre-dependent, Tet-controllable histone deacetylation tool strain with dual fluorescent reporters, created by targeted insertion at the Igs7 locus (TIGRE). Exposure to Cre recombinase removes both STOP cassettes, resulting in tTA2 expression, robust tdTomato fluorescence and EGFP/HDAC1 fusion protein expression. HDAC1 is a potent epigenetic regulator and its overexpression will promote histone deacetylation. EGFP/HDAC1 expression may be expected to be diminished/eliminated by doxycycline.