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  • C57BL/6-Tmem119em1(cre/ERT2)

    产品型号:GM-J#031820 -Available

    产品应用:Tmem119-2A-CreERT2 knock-in mice have the endogenous transmembrane protein 119 (Tmem119) promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase primarily in microglia, and are also designed to retain endogenous Tmem119 expression. These mice allow specific and inducible genetic manipulations in vivo for studying the function of resident microglia in the central nervous system during neuroinflammatory and neurological disease/injury, and may also be useful for investigating bone development, osteoblast differentiation and osteosarcoma.

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