产品型号：GM-J#031671 -Cryorecovery

产品应用：These GFAP.tTA.TRE.Flag.HMOX1 mice express human heme oxygenase 1 (HMOX1) in astrocytes under the control of the Tet-Off system (removal of doxycycline from diet initiates transgene expression), resulting in 1.4 to 5.8-fold increase in total of heme oxygenase 1 protein in astrocytes. Depending on the window of gene expression, these double transgenic mice exhibit inducible locomotor impairment, stereotypy, and mitochondrial damage & autophagy. They are suitable for use in applications related to the study of oxidative stress in the brain, neurodevelopment and neurodegenerative diseases.