产品型号：GM-J#031569 -Cryorecovery

产品应用：Ai169(TIT2L-ASAP2s-ICL-tTA2)-D (or Ai169D) mice are a Cre/Tet-dependent, voltage-sensitive, fluorescent line - created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Exposure to Cre recombinase removes both STOP cassettes - resulting in expression of tTA2 and ASAP2s (green fluorescent voltage indicator with high sensitivity). ASAP2s expression may then be diminished by doxycycline. Ai169D mice may be useful for in vivo imaging of voltage dynamics.