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  • B6.Cg-Gt(ROSA)26Sortm1.1(CAG-Pycard/mCitrine*,-CD2*)Dtg/J

    产品型号:GM-J#030744 -Available

    产品应用:The constitutively-expressed R26-CAG-ASC-citrine allele has the Gt(ROSA)26Sor locus and CAG promoter directing widespread expression of a fluorescent adaptor fusion protein (ASC-citrine) that retains the function of endogenous ASC - forming assembled inflammasome complexes (specks) upon exposure to inflammasome activator(s) both in vitro and in vivo. These R26-CAG-ASC-citrine mice are a fluorescent reporter of inflammasome complex activation.

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