产品型号：GM-J#030743 -Cryorecovery

产品应用：The R26-CAG-LSL-ASC-citrine floxed allele has a CAG promoter and loxP-flanked STOP cassette upstream of the ASC-citrine fusion protein, all inserted into the Gt(ROSA)26Sor locus. Following removal of the floxed-STOP cassette, they express a fluorescent adaptor fusion protein (ASC-citrine) that retains the function of endogenous ASC - forming assembled inflammasome complexes (specks) upon exposure to inflammasome activator(s) both in vitro and in vivo. These R26-CAG-LSL-ASC-citrine mice are a Cre recombinase-dependent fluorescent reporter of inflammasome complex activation.