产品型号：GM-J#030216 -Cryorecovery

产品应用：Ai136(TITL-ReaChR-YFP)-D (also called Ai136D) mice are a Cre/Tet-dependent, optogenetic line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Following Cre-mediated removal of the STOP cassette, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of the channelrhodopsin/EYFP fusion protein (ReaChR/EYFP). Subsequent illumination of ReaChR-expressing (EYFP fluorescent) cells with orange-to-red light leads to reversible photostimulation of action potential firing/neural activity in these cells.