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  • B6.Cg-Gt(ROSA)26Sortm2(CAG-rtTA3,-mKate2)Slowe/J

    产品型号:GM-J#029633 -Available

    产品应用:CAGs-LSL-RIK (or Rosa26-CAGs-LSL-RIK) knock-in has a CAG promoter and loxP-flanked STOP cassette upstream of the third-generation reverse tetracycline-regulated transactivator gene (rtTA3), IRES sequence and the monomeric far-red fluorescent protein mKate2, all inserted into the Gt(ROSA)26Sor locus. These mice are a Cre recombinase-dependent, Tet-On and fluorescent tool strain - following removal of the floxed-STOP cassette, they allow dox-conditional expression of TRE promoter-driven target genes in conjunction with mKate2 fluorescence.

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