产品型号：GM-J#029124 -Cryorecovery

产品应用：These mice carry the Gba1tm1.1Mjff allele (Stock No. 019106) and the Tg(Thy1-SNCA)15Mjff transgene (Stock No. 017682). They have applications related to Parkinson's disease, Gaucher disease and synucleinopathies, and neurodegeneration elicited by the aggregation of SNCA. While increased SCNA pathology and grip strength reductions are observed in this model, the nigrostriatal system remains largely intact. Neuroinflammation is not exacerbated by the GBA D409V mutation.