产品型号:GM-J#026944 -Cryorecovery
产品应用:The RC::L-DTA allele has a cre-dependent FLEx switch containing an eGFP sequence and an inverted tox176 attenuated diphtheria toxin subunit alpha gene (DTA*G128D) that are uniquely flanked/separated by inward-facing lox sites (both lox2272 and loxP). Widespread eGFP fluorescence is observed in the absence of Cre recombinase. Subsequent exposure to Cre recombinase that places the DTA*G128D into the proper orientation for expression results in ablation of those cells.