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  • B6.Cg-Gt(ROSA)26Sortm1.1(CAG-tdTomato,-EGFP)Pjen/J

    产品型号:GM-J#026930 -Cryorecovery

    产品应用:The RC::RFLTG triple-recombinase responsive indicator allele is designed with a rox-flanked STOP, frt-flanked STOP and loxP-flanked tdTomato::STOP all preventing transcription of eGFP. Dre- and FLP-recombinase result in high tdTomato fluorescence, and further exposure to Cre recombinase results in robust eGFP fluorescence. The RC::RFLTG allele and its derivatives (e.g., dual-recombinase responsive and single-recombinase responsive) are useful for fluorescent labeling of cells/tissues in embryonic or adult mice. These mice allow intersectional genetic fate mapping of different cell subpopulations defined by the overlap of three gene expression domains.

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