产品型号：GM-J#023529 -Cryorecovery

产品应用：Ai79(TITL-Jaws)-D (also called Ai79D) mice are a Cre/Tet-dependent, optogenetic line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Following Cre-mediated removal of the STOP cassette, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of an improved Halorhodopsin/EGFP fusion protein (Halo57*K200R*W214F/EGFP or Jaws). Subsequent illumination of Jaws-expressing (EGFP fluorescent) cells with yellow-to-red light leads to reversible photoinhibition of action potential firing/neural activity in these cells.