产品型号：GM-J#021461 -Cryorecovery

产品应用：The MADM-12TG (Igs6TG) allele has the CMV enhancer/chicken beta-actin core promoter, the N-terminal portion of tdTomato, a beta-globin intronic sequence (containing an frt site and loxP site), and the C-terminal portion of mut4-EGFP all inserted into the Igs6 locus on chromosome 12 (~1.71 cM; ~16 kbp downstream of exon 1 of the Rab10 gene). These MADM-12TG mutants are designed for MADM (mosaic analysis with double markers), and must be crossed to MADM-12GT mice harboring a reciprocal mutation at the same locus (Stock No. 021460). This MADM system allows Cre recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation, mitosis, and imprinting.