产品型号：GM-J#017921 -Cryorecovery

产品应用：The R26TG allele has a CMV enhancer/chicken beta-actin core promoter-driven "MADM TG" cassette (ATG-intron-GFPC-terminus) inserted into the Gt(ROSA)26Sor locus on chromosome 6. The new TG cassette in R26TG mice is compatible with any "GX cassette" (GFPN-terminus-intron-XATG-less) where XATG-less is any gene without the start codon. Like the original MADM system, the "new MADM-6" system provides a tool to generate genetic mosaics in which an individual organism contains somatic cells of different genotypes. This allows Cre or FLP recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation and mitosis, as well as for the MADM-Tet system.