产品型号：GM-J#017915 -Cryorecovery

产品应用：The PRCre knockin allele harbors an internal ribosome entry site and Cre recombinase gene downstream of the progesterone receptor (Pgr or PR) transcriptonal stop codon. As such, Cre recombinase expression is directed to Pgr-expressing cells by the endogenous promoter/enhancer elements of the progesterone receptor locus. These PRCre knockin mice may be useful for studying the function of this ligand-inducible transcription factor in progesterone-responsive cells/tissues such as uterus, ovary, oviduct, pituitary gland, and mammary gland. They may also be useful for studying sexually dimorphic nuclei in the hypothalamus and steroid hormone-induced malignancies.