产品型号：GM-J#016223 -Available

产品应用：Phox2b-Cre BAC transgenic mice have Cre recombinase expression directed primarily to the hindbrain by the Phox2b promoter/enhancer regions, and may be used to generate conditional mutations for studying neuronal cell types expressing or depending on the Phox2b transcription factor. Specifically, these mice may be useful for studying human respiratory disease, central chemoreceptive neurons in the retrotrapezoid nucleus, respiratory rhythmogenesis, and autonomic nervous system dysregulation (such as congenital central hypoventilation syndrome (CCHS) or Ondine-Hirschsprung disease).