产品型号：GM-J#012621 -Cryorecovery

产品应用：These α3[5] mice contain a mutation designed to introduce 5 nucleotide mutations to exon 5 of mouse nicotinic acetylcholine receptor (nAChR) neuronal α3 subunit and a loxP-flanked neomycin (neo) resistance cassette upstream of exon 5. These mice may be useful for studying the pathological mechanisms of receptor assembly and trafficking in neurological and psychiatric disorders including Alzheimer's disease, Parkinson's disease, schizophrenia, and epilepsy, as well as drug addiction, response to pain, and nicotine induced behaviors.