产品型号：GM-J#012467 -Cryorecovery

产品应用：These BAC Lrrk2-G2019S mice express a mutant form of mouse leucine-rich repeat kinase 2 (Lrrk2-G2019S) associated with autosomal dominant, late-onset Parkinson's disease directed by the endogenous Lrrk2 promoter/enhancer regions on the BAC transgene. These mice have reduced striatal dopamine content and may be useful for studying Parkinson's disease pathogenesis and neurodegeneration elicited by the dominant toxic effects of mutant LRRK2-G2019S expression.