产品型号:GM-J#012343 -Cryorecovery
产品应用:The R26StopFLP110* conditional allele is targeted to the Gt(ROSA)26Sor locus and has a loxP-flanked Neo-STOP cassette preventing transcription of the phosphatidylinositol 3-kinase, catalytic, alpha polypeptide gene (Pik3ca or P110α) and EGFP. These R26StopFLP110* mice allow inducible expression of activated PIK3 heterodimer activity and may be useful in studying signaling cascades that control cell survival, growth, and proliferation, as well as differentiation, regeneration, hypertension and cancer.