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  • B6.Cg-Tg(Tyr-cre/ERT2)

    产品型号:GM-J#012328 -Cryorecovery

    产品应用:Tyr::CreERT2 mice have expression of CreERT2 fusion protein directed by mouse tyrosinase promoter/enhancer regions. When bred with mice containing loxP-flanked sequences, tamoxifen/4-hydroxytamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in the Tyr-expressing cells of the offspring. These Tyr::CreERT2 mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in melanocytes/melanoblasts.

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