产品型号:GM-J#010987 -Cryorecovery
产品应用:These Sox18-GCE mutant mice have a tamoxifen inducible Cre-mediated recombination system. A GFP-Cre/ERT2 cassette (GCE) was inserted into the Sox18, SRY-box containing gene 18, locus. Following tamoxifen administration green fluorescence is detected in the kidneys and ovary of E15.5 heterozygous embryos and Cre recombinase activity is detected in a low percentage of cells in the kidney from E15.5 heterozygous embryos. This mutant mouse strain may be useful in studies of genitourinary system development.