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  • STOCK Wt1tm2(cre/ERT2)

    产品型号:GM-J#010912 -Available

    产品应用:The Wt1CreERT2 knock-in/knock-out allele both abolishes Wilms tumor 1 homolog gene function and directs expression of the CreERT2 fusion protein to proepicardium and epicardium by the Wt1 promoter/enhancer elements. As Wt1 is expressed in the developing genitourinary system and in the mesothelia overlying most visceral organs, these mutant mice are useful as a tamoxifen-inducible Cre-lox tool for lineage-tracing/marking Wt1-expressing cells for studying cardiomyocytes in the developing heart.

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